How fluorescence is transforming the operating room – Clinically, economically, and ecologically

Fluorescence is transforming the operating room

At the 2025 joint symposium of NVEC and DFGS, leading Dutch experts shared how fluorescence imaging is expanding its role in surgical practice. From its clinical value in visualizing anatomical structures, tissue perfusion and tumour imaging to its impact on sustainability and cost reduction, fluorescence is rapidly transitioning from innovation to implementation.

In this blog, we highlight key takeaways from the symposium — and explore how this powerful technology is reshaping precision surgery in the Netherlands and beyond.

🔬 The Power of ICG: Clinically Proven and Heading Towards the Guidelines

A central theme throughout the symposium was the growing use of Indocyanine Green (ICG) across a wide range of surgical procedures. ICG is increasingly moving towards becoming a guideline-worthy tool in surgery — particularly for sentinel lymph node biopsy (SLNB) in breast cancer and ICG angiography in (acute) mesenteric ischaemia.

Speaker after speaker confirmed what many are already seeing in practice: fluorescence imaging is widely applicable, intuitive to use, and has a positive impact on patient care.

More Than Clinical Benefit: Economic and Environmental Impact🍃💶

Another key takeaway from the symposium: ICG does more than support clinical decision-making — it also offers economic and environmental advantages.

In the Netherlands alone, an estimated 235 anastomotic leaks could be prevented annually through the use of ICG. This translates into average savings of around €30,000 per patient, thanks to reduced ICU stays, fewer reinterventions and shorter hospital admissions.

The environmental savings are equally striking. A single anastomotic leak is associated with:

With ICG, we’re not only improving outcomes — we’re also helping create a more sustainable healthcare system. And the impact doesn’t stop at bowel surgery: similar gains can be seen in amputation procedures and sentinel node biopsies.

The next step? Mapping the production and lifecycle impact of ICG itself, so we can understand the full picture.

🚀Innovation in Full Swing: Paediatrics, Tumour Imaging and AI

In addition to well-established indications, the symposium also highlighted new and emerging domains for fluorescence imaging:

  • Paediatric surgery, such as identifying and assessing the perfusion of parathyroid glands in children.
  • New tumour-specific tracers, like Bevacizumab-800CW for breast cancer, which allow surgeons to receive intraoperative feedback on resection margins and residual tumour presence.
  • During the evening session of the Dutch Association of Surgery (NVvH), the spotlight was firmly on AI in surgery — with real-time, image-guided decision-making at the heart of future operating theatres.

🎓 The Key to Progress: Implementation and Education

The technology is here. The first successes are clear. Now is the time to scale up the use of fluorescence imaging — and that requires:

  • Training of surgical teams
  • Hands-on workshops and online learning programmes

At Mobula, we support hospitals, training centres and distributors with a structured implementation workflow and practical tools to integrate ICG successfully and responsibly.

🤝 Collaboration Fuels Implementation & Innovation

The NVEC & DFGS Symposium showed just how powerful innovation can be when science, clinical practice and industry work together.

Are you ready to explore how fluorescence can benefit your team or hospital?

👉 Explore Mobula Academy training programme, or get in touch for tailored support.

Keep an eye on our website and LinkedIn to stay up to date about these exciting insights and innovations!

Picture of Nanne Duijnkerke

Nanne Duijnkerke

As Manager of Training and Marketing, Nanne Duijnkerke is committed to equipping practitioners with comprehensive training, empowering them to master Fluorescence-Guided Surgery (FGS) and seamlessly integrate it into their daily practice. With her energy, collaborative spirit, and dedication to share expertise, she ensures FGS becomes part of every surgeon’s toolbox.
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Fluorescence is transforming the operating room — clinically, economically, and ecologically. During innovation symposium NVEC/DFGS