Indocyanine Green Angiography (ICGA) is the gold standard in diagnosing a number of serious eye conditions and is a key diagnostic tool used by ophthamology specialists worldwide. ICGA is particularly useful in the differential diagnosis of Polypoidal Choroidal Vasculopathy (PCV), Central Serous Chorioretinopathy (CSCR), and Retinal Angiomatous Proliferation (RAP), which can be misdiagnosed as nAMD (Neovascular Age-related Macular Degeneration)1
The retention of ICG in the fenestrated choroidal circulation, combined with its low permeability, makes ICG angiography ideal for viewing the choroidal blood vessels. Once injected, Verdye binds to plasma proteins and quickly circulates to the choroid layer, delineating the choroidal veins within 15-20 secs.
ICG imaging is an essential requirement for specialised retinal clinics at tertiary referral hospital eye services”
THE ROYAL COLLEGE OF OPHTHALMOLOGISTS2
1 Amoaku WM, Chakravarthy U, Gale R, Gavin M, Ghanchi F, Gibson J et al. Defining response to anti VEGF therapies in neovascular AMD. Eye (London) 2015.
2Ophthalmic Services Guidance Ophthalmic Imaging, November 2016, The Royal College of Ophthalmologists 2016
